pCPA methyl ester hydrochloride

Research use only, not for human use.

pCPA methyl ester hydrochloride is an inhibitor of tryptophan hydroxylase inhibitor and 5-HT synthesis. pCPA methyl ester hydrochloride is permeable across the blood-brain barrier and reduces 5-HT central availability.

pCPA methyl ester hydrochloride is an inhibitor of tryptophan hydroxylase inhibitor and 5-HT synthesis. pCPA methyl ester hydrochloride is permeable across the blood-brain barrier and reduces 5-HT central availability.(In Vivo):In C57BL/6 elite male mice, 5-HT levels decreased by 85% and 55% in the hippocampus of mice treated with oral or i.p. PCPA methyl ester hydrochloride(250, 500 mg/kg), respectively, whereas in the prefrontal cortex, 5-HT levels decreased by 65% and 50%.

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Animal Model:C57BL/6 elite male mice (3 months old)Dosage:500 mg/kg per day for the first 2 days and 250 mg/kg for the rest of the treatment. Administration:Oral administration; daily; for 8 weeksResult:Serotonin levels were significantly decreased in both hippocampus and cortex.

4-Chloro-DL-phenylalanine methyl ester hydrochloride

Endocrinology/Hormones

5-HT Receptor

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14173-40-1

250.12

C10H13Cl2NO2

>98% (HPLC)

In Vitro:?H2O : 50 mg/mL (199.90 mM)

Cl.COC(=O)[C@@H](N)Cc1ccc(Cl)cc1

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(-20℃)

With Ice Pack

≥ 2 years